Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders

Vascular endothelial growth factors (VEGFs) are key mediator of retinal and choroidal neovascularization as well vascular leakage leading to macular edema. As such, VEGF plays an important role in mediating visually significant complications associated with common disorders such diabetic retinopathy, vein occlusion, age-related degeneration. Various drugs that inhibit (anti-VEGF therapies) have been developed minimize vision loss these disorders. These injected into the vitreous cavity a clinic setting at regular intervals. This article provides overview various anti-VEGF used ophthalmology conditions benefit from this therapy.